Activated charcoal for acute overdose: a reappraisal
نویسندگان
چکیده
منابع مشابه
Activated charcoal for acute overdose: a reappraisal.
Sometimes mistakenly characterized as a 'universal antidote,' activated charcoal (AC) is the most frequently employed method of gastrointestinal decontamination in the developed world. Typically administered as a single dose (SDAC), its tremendous surface area permits the binding of many drugs and toxins in the gastrointestinal lumen, reducing their systemic absorption. Like other decontaminati...
متن کاملIndications for single-dose activated charcoal administration in acute overdose.
PURPOSE OF REVIEW Gastrointestinal decontamination in overdose patients remains a controversial problem in emergency medicine. There has been a significant decrease in the use of single-dose activated charcoal (SDAC) in recent years based on little new evidence and possibly because the overall mortality in overdose patients is low. RECENT FINDINGS Human volunteer studies suggest SDAC is effec...
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It is common practice to try to prevent intestinal absorption of ingested poisons. Controversy continues about the relative effectiveness of charcoal, ipecacuanha, and lavage in salicylate overdose,' but no study has yet compared all three methods. This study of simulated aspirin overdose in volunteers aimed to compare the effectiveness of gastric lavage, emesis induced by ipecacuanha, and acti...
متن کاملA randomized clinical trial of activated charcoal for the routine management of oral drug overdose.
BACKGROUND Activated charcoal (AC) is commonly used for the routine management of oral drug overdose. AIM To determine whether the routine use of activated charcoal has an effect on patient outcomes. DESIGN Randomized controlled unblinded trial. METHODS We recruited all adult patients presenting with an oral overdose at The Canberra Hospital, excluding only transfers, late presenters, tho...
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Serious complications after carbamazepine poisoning, such as coma, seizures, respiratory failure, cardiac conduction abnormalities, and death are more likely with serum levels greater than 170 micromol L(-1). We report a case of a single massive carbamazepine overdose in a 19-year-old male, following attempted suicide, without prior history of seizure disorder. On admission, three hours after i...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2015
ISSN: 0306-5251
DOI: 10.1111/bcp.12793